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Matthew C Wright Selected Research

Ionic Liquids

1/2021The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver.
11/2020Emerging risk from "environmentally-friendly" solvents: Interaction of methylimidazolium ionic liquids with the mitochondrial electron transport chain is a key initiation event in their mammalian toxicity.
10/2020Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse.
2/2020The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects.
1/2020Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids.

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Matthew C Wright Research Topics

Disease

9Fibrosis (Cirrhosis)
05/2017 - 01/2005
8Liver Diseases (Liver Disease)
01/2021 - 04/2008
6Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
01/2021 - 01/2017
6Liver Cirrhosis (Hepatic Cirrhosis)
01/2016 - 07/2004
5Inflammation (Inflammations)
05/2017 - 03/2010
2Infections
12/2019 - 02/2016
2Reperfusion Injury
12/2019 - 01/2015
2Adenocarcinoma
10/2018 - 07/2018
2Cicatrix (Scar)
01/2016 - 04/2008
2Death (Near-Death Experience)
01/2015 - 08/2013
2Necrosis
05/2005 - 07/2004
1Body Weight (Weight, Body)
10/2020
1Chronic Disease (Chronic Diseases)
01/2020
1Pathologic Constriction (Stenosis)
12/2019
1Mycoses (Diseases, Fungus)
11/2017
1Hemolysis
11/2017
1Cholangiocarcinoma
01/2016
1Wounds and Injuries (Trauma)
01/2015
1Cholestasis
01/2015
1Breast Neoplasms (Breast Cancer)
02/2014
1Weight Loss (Weight Reduction)
09/2010
1Chemical and Drug Induced Liver Injury
05/2010
1Weight Gain
08/2009
1Liver Failure
04/2008

Drug/Important Bio-Agent (IBA)

5Ionic LiquidsIBA
01/2021 - 01/2020
3Messenger RNA (mRNA)IBA
07/2018 - 01/2005
3Pharmaceutical PreparationsIBA
01/2015 - 12/2008
3Pregnane X ReceptorIBA
01/2015 - 05/2005
21-octyl-3-methylimidazoliumIBA
11/2020 - 10/2020
2XenobioticsIBA
11/2018 - 01/2017
2Proteins (Proteins, Gene)FDA Link
02/2014 - 04/2008
2GliotoxinIBA
07/2008 - 07/2004
2Carbon Tetrachloride (Tetrachloromethane)IBA
05/2005 - 01/2005
1Indicators and Reagents (Reagents)IBA
12/2019
1AntibodiesIBA
11/2018
1Mitochondrial Proteins (Mitochondrial Protein)IBA
11/2018
1Thioctic Acid (Lipoic Acid)IBA
11/2018
1Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA
11/2018
1Hepatocyte Nuclear Factor 4IBA
10/2018
1TransposasesIBA
10/2018
1Dexamethasone (Maxidex)FDA LinkGeneric
07/2018
1Carcinoembryonic AntigenIBA
07/2018
1Cytochrome P-450 CYP3AIBA
07/2018
1NitrogenIBA
11/2017
1Amphotericin B (Amphotericin)FDA LinkGeneric
11/2017
1CreatinineIBA
11/2017
1Urea (Carbamide)FDA LinkGeneric
11/2017
1Bile Acids and Salts (Bile Acids)IBA
05/2017
1SulfotransferasesIBA
05/2017
1TartrazineIBA
05/2017
1Alkaline PhosphataseIBA
05/2017
1Interleukin-10 (Interleukin 10)IBA
02/2016
1CytokinesIBA
02/2016
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2016
1Interleukin-6 (Interleukin 6)IBA
02/2016
1Interleukin-2 (IL2)IBA
02/2016
1estragole (methyl chavicol)IBA
01/2016
11'-hydroxyestragoleIBA
01/2016
1LipidsIBA
01/2016
1Liposomes (Liposome)IBA
01/2016
1Immunoglobulin FragmentsIBA
01/2016
1IsoprostanesIBA
01/2015
1Member 11 Subfamily B ATP Binding Cassette TransporterIBA
02/2014
1Multidrug Resistance-Associated ProteinsIBA
02/2014
1EnzymesIBA
09/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010
1Tacrolimus (Prograf)FDA LinkGeneric
05/2010
1Cyclosporine (Ciclosporin)FDA LinkGeneric
05/2010
1Floxacillin (Flucloxacillin)IBA
05/2010
1NF-kappa B (NF-kB)IBA
03/2010
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
08/2009
1Keratin-7 (Cytokeratin 7)IBA
08/2009
1GlucocorticoidsIBA
08/2009
1Ligases (Synthetase)IBA
08/2009
1Carbamyl Phosphate (Carbamoyl Phosphate)IBA
08/2009
1Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA
08/2009
1LigandsIBA
05/2009
1Membrane Proteins (Integral Membrane Proteins)IBA
07/2008
1Rifampin (Rifampicin)FDA LinkGeneric
07/2006
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2006
1PregnenoloneIBA
05/2005
1Pregnenolone Carbonitrile (PCN)IBA
05/2005
1ProcollagenIBA
01/2005
1Tissue Inhibitor of Metalloproteinase-1IBA
01/2005
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
01/2005
1Actins (F Actin)IBA
01/2005
1Phosphotransferases (Kinase)IBA
01/2005
1Sulfasalazine (Azulfidine)FDA LinkGeneric
01/2005
1Sulfhydryl Compounds (Thiols)IBA
07/2004
1AntioxidantsIBA
07/2004

Therapy/Procedure

4Therapeutics
01/2016 - 04/2008
3Liver Transplantation
12/2019 - 12/2008
1Intraperitoneal Injections
10/2020
1Ligation
01/2016
1Warm Ischemia
08/2013